MegaSporeBiotic

MegaSporeBiotic

 (3,636 Reviews)
$52.49
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A 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. This unique all-spore formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria.

MegaSporeBiotic does not require refrigeration and maintains a healthy gut microbiome.

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MegaSporeBiotic

MegaSporeBiotic

$52.49
$52.49 $66.25
SAVE 20% Sold out
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Microbiome Labs is innovating wellness solutions by restoring balance and diversity in the microbiome for whole-body restoration.

  • Science-Driven

    A balance of biological innovation and scientific validation


  • Probiotic Pioneers

    Originators of clinically validated spore-based probiotics


  • Innovative Biotechnology

    Evidence-based solutions that help enhance care across health categories

  • Microbiome Optimization

    Committed to whole health through balance and restoration of the gut

    At a glance

    MegaSporeBiotic is a probiotic blend of 5 Bacillus spores that have been shown to maintain healthy gut barrier and immune function. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract.

    Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims to RECONDITION the gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. MegaSporeBiotic has quickly become a household favorite among health practitioners and consumers alike.

    TrustScore Verified by SuppCo

    TrustScore is a clear and unbiased way to measure the quality of your supplements. SuppCo’s proprietary rating system scores products on a 10-point scale based on their ability to deliver against 29 key quality attributes.

    Ingredients and formula

    With the launch of MegaSporeBiotic™, Microbiome Labs completely disrupted the probiotic industry, shifting the focus from reseeding to reconditioning the gut microbiome with the help of Bacillus spores.

    Bacillus Licheniformis

    Produces proteases that aid protein digestion
    Produces full spectrum of B vitamins

    Bacillus Indicus HU36

    Produces carotenoids: lycopene, astaxanthin, beta-carotene, and lutein
    Produces quinols and vitamins

    Bacillus Subtilis HU58

    Produces nattokinase and vitamin K2
    Supports healthy GALT development

    Bacillus Clausii

    Supports immune function

    Bacillus Coagulans

    Produces L+ optical form of lactic acid
    Supports immune function

    Total Gut Restoration Studies

    Form/Duration

    Study Details and Results

    Reference

    Total Gut Restoration

    in vitro (M-SHIME®)

    Fecal samples were used in vitro to evaluate the effects on the gut microbiome using the Total Gut Restoration supplementation system. TGR supplementation resulted in short-chain fatty acids (SCFAs) production and supported intestinal barrier function and immune function.

    DOI: 10.2217/fmb-2022-0066

    MegaSporeBiotic™ and MegaMucosa™

    The combination of MegaSpore™ and MegaMucosa™ promoted immune function and provided support to colonic mucosa.

    DOI: 10.3390/nu12123607

    MegaSporeBiotic™

    10 days

    300 million CFU of MegaSporeBiotic™ supplementation supported immune function and iron levels in mice.

    DOI: 10.1002/jpen.1851

    MegaSporeBiotic™

    12 weeks

    12 weeks of supplementation with MegaSporeBiotic™ supported triglyceride levels in study subjects.

    PMID: 33041703

    MegaSporeBiotic™

    Administration of MegaSporeBiotic™ was shown to support liver function.

    DOI: 10.3390/nu12030632

    MegaSporeBiotic™

    60 days

    MegaSporeBiotic™ provided relief for occasional abdominal discomfort and supported elimination and digestive health in study subjects.

    DOI: 10.3390/nu11091968

    (continued):

    Form/Duration

    Study Details and Results

    Reference

    MegaSporeBiotic™

    30 days

    MegaSporeBiotic™ demonstrated cardiac-supportive and immune-supportive properties.

    DOI: 10.4291/wjgp.v8.i3.117

    MegaSporeBiotic™ and MegaPre™

    MegaSporeBiotic™ and MegaPre™ promoted microbial diversity in the transverse and descending colon. Additionally, this synbiotic combination promoted the production of all SCFAs in the gut, including acetate, propionate, and butyrate.

    DOI: 10.1016/j.ijpx.2019.100021

    MegaSporeBiotic™

    3 weeks

    MegaSporeBiotic promoted bacterial diversity and supported ammonia, propionate, and lactate levels.

    DOI: 10.1016/j.foodres.2021.110676

    MegaSporeBiotic™ and antibiotics

    MegaSporeBiotic™ was shown to support immune system health and help maintain normal intestinal flora.

    DOI: 10.3390/microorganisms10061178

    Dosing instructions

    Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.

    01 Week 1

    1 capsule every other day

    02 Week 2

    1 capsule daily

    03 Week 3+

    2 capsules daily

    If 1 capsule every other day causes side effects, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible side effects may include abdominal cramping, loose stools, and changes in bowel movements. Though these side effects may be uncomfortable, they are a sign that the product is working! Side effects should resolve within 2-3 days.